It is concentrated blood plasma which contains approximately three to five times the number of platelets found in normal circulating blood. In addition, it contains platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), transforming growth factor (TGF) and other bioactive proteins that aid in wound healing and possibly hair growth.
Human blood is comprised primarily of red blood cells (RBC), as well as white blood cells (WBC), platelets, and plasma. It is thought that by increasing the platelet count in a wounded area, the body’s healing to that area would be accelerated – explaining the use of PRP (platelet-rich-plasma) in wound healing. Its possible effects on promoting hair growth would make it potentially useful in both hair transplantation and the medical treatment of hair loss.
PRP Therapy in Hair Transplant
Hair follicles survive through the absorption of oxygen from surrounding tissue. It is conjectured that the introduction of platelets and white blood cells through platelet-rich-plasma (PRP) would amplify the body’s naturally occurring wound healing mechanism. It is also proposed that PRP can actually stimulate the stem cells (dermal papilla) of the newly transplanted hair follicles.
The concentrated form of plasma has been shown to accelerate wound healing and tissue repair and, thus, could potentially benefit hair restoration procedures. In hair transplantation, PRP can be injected into or sprayed on the recipient site area to, theoretically, stimulate the healing of the transplanted grafts and into the donor area to facilitate healing of the donor incision and potentially minimize scar formation.
In the medical treatment of male and female pattern baldness (androgenetic alopecia), PRP can be injected into the balding scalp to potentially stimulate thin (miniaturized) hair to grow into thicker (terminal) hairs. Patients with thin, but not totally bald areas, would be the best candidates.