PRP with stem cells (stromal vascular factor SVF) for treatment of Androgenetic Alopecia
Regenerative therapies using high density PRP and SVF are novel treatment modalities.
The potential use of adult stem/ stromal cells for providing separative and healing cells, and tissues for cell- based therapies is enormous. Cell- based therapies include treatment protocol in which stem/ stromal cells may be induced by their environment (niche) to differentiate into specific cell types required to repair damage cells or tissues or provide chemical signaling (Paracrine) to accomplish wound site or tissue regeneration. Many cell- based therapies use fundamental pathways and are used in homeostasis and repair of cells and tissues. There are numerous clinical reports and monitored trails already in place. These studies have emerged with an excellent record in regard to patient safety and clinical efficacy. These studies utilize adult derived melancholy stem / stromal cells (MSCs) which are found in essentially all vascularized tissues. In particularly, MSCs are found in high numbers in the body’s largest micro vascular structure i.e. adipose tissue. The adult adipose- derived stromal tissue complex contains multi potent heterogeneous cellular population that has been demonstrated to influence undifferentiated stromal cells and precipitate cellular activation, proliferation and regeneration at “site specific’ region or “niche”. Existing research on the use of adipose- derived regenerative cells (ADRCs) and stromal vascular fraction (SVF) and its effect on hair growth is not fully understood or elucidated. Current opinion within the adipose stem /stromal cell science societies is the micro environment (niche) of the follicles may be influenced by bio cellular products and the adipose- derived tissue stromal complex.